Anti-CDK1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CDK1

Immunogen :

A synthetic peptide of human CDK1

Synonym :

CDC2;CDC28A;P34CDC2

Isotype :

IgG

Gene ID :

983

Clone No :

Swiss Port :

P06493

Molecular weight :

34kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:200-1000. IHC 1:10-100.

Subcellular location :

Cytoplasm Mitochondrion Nucleus centrosome cytoskeleton microtubule organizing center spindle

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.