PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
NPPBImmunogen :
A synthetic peptide of human NPPBSynonym :
BNPIsotype :
IgGGene ID :
4879Clone No :
Swiss Port :
P16860Molecular weight :
15kDaPurification :
Affinity purificationReactivity :
HumanApplication :
IHCRecommended dilution :
IHC 1:25-100.Subcellular location :
CytoplasmStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.RELATED PRODUCTS
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REFERENCE LIBRARY
No data