Anti-RHOB Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

RHOB

Immunogen :

A synthetic peptide of human RHOB

Synonym :

ARH6;ARHB;MST081;MSTP081;RHOH6

Isotype :

IgG

Gene ID :

388

Clone No :

Swiss Port :

P62745

Molecular weight :

22kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Cell membrane Endosome Membrane Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.