Anti-FLT1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

FLT1

Immunogen :

A synthetic peptide of human FLT1

Synonym :

FLT;FLT-1;VEGFR1;VEGFR-1

Isotype :

IgG

Gene ID :

2321

Clone No :

Swiss Port :

P17948

Molecular weight :

150kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

IF

Recommended dilution :

IF 1:100-500.

Subcellular location :

Plasma membrane Endosome secreted Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.