PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
RAB3IPImmunogen :
Recombinant protein of human RAB3IPSynonym :
RABIN3;RABIN8Isotype :
IgGGene ID :
117177Clone No :
Swiss Port :
Q96QF0Molecular weight :
53kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
IHCRecommended dilution :
IHC 1:25-100.Subcellular location :
Cell projection Cytoplasm Nucleus cytoskeleton lamellipodiumStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data