Anti-C8orf4 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

C8orf4

Immunogen :

Recombinant protein of human C8orf4

Synonym :

TC1;TC-1

Isotype :

IgG

Gene ID :

56892

Clone No :

Swiss Port :

Q9NR00

Molecular weight :

12kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

IHC

Recommended dilution :

IHC 1:25-100.

Subcellular location :

Cytoplasm Nucleus Nucleus speckle nucleolus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.