Anti-TIMM8A Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TIMM8A

Immunogen :

Recombinant protein of human TIMM8A

Synonym :

DDP;MTS;DDP1;DFN1;TIM8

Isotype :

IgG

Gene ID :

1678

Clone No :

Swiss Port :

O60220

Molecular weight :

11kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Intermembrane side Mitochondrion inner membrane Peripheral membrane protein

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.