Anti-COPS6 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

COPS6

Immunogen :

Full length fusion protein

Synonym :

CSN6;MOV34-34KD

Isotype :

IgG

Gene ID :

10980

Clone No :

Swiss Port :

Q7L5N1

Molecular weight :

36kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

IHC

Recommended dilution :

IHC 1:20-100.

Subcellular location :

Nucleus Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.