Anti-CETN3 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CETN3

Immunogen :

Full length fusion protein

Synonym :

CEN3;CDC31

Isotype :

IgG

Gene ID :

1070

Clone No :

Swiss Port :

O15182

Molecular weight :

20kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB IHC

Recommended dilution :

WB 1:500-2000. IHC 1:25-100.

Subcellular location :

Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center nucleolus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.