Anti-SQSTM1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

SQSTM1

Immunogen :

A synthetic peptide of human SQSTM1

Synonym :

p60;p62;A170;DMRV;OSIL;PDB3;ZIP3;p62B;NADGP;FTDALS3

Isotype :

IgG

Gene ID :

8878

Clone No :

Swiss Port :

Q13501

Molecular weight :

48kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

IHC

Recommended dilution :

IHC 1:25-100.

Subcellular location :

Cytoplasm Cytoplasmic vesicle Endoplasmic reticulum Late endosome Lysosome Nucleus P-body autophagosome

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.