Anti-CPE Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CPE

Immunogen :

Recombinant protein of human CPE

Synonym :

CPH

Isotype :

IgG

Gene ID :

1363

Clone No :

Swiss Port :

P16870

Molecular weight :

53kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:25-100.

Subcellular location :

Cytoplasmic vesicle Nucleus Peripheral membrane protein Secreted secretory vesicle membrane

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes.