Anti-BTK Polyclonal Antibody

No :   K007282P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

BTK

Immunogen :

Recombinant protein of human BTK

Synonym :

AT;ATK;BPK;XLA;IMD1;AGMX1;PSCTK1

Isotype :

IgG

Gene ID :

695

Clone No :

Swiss Port :

Q06187

Molecular weight :

76/80kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

IHC

Recommended dilution :

IHC 1:25-100.

Subcellular location :

Cell membrane Cytoplasm Nucleus Peripheral membrane protein

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
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REFERENCE LIBRARY
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