PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
BTKImmunogen :
Recombinant protein of human BTKSynonym :
AT;ATK;BPK;XLA;IMD1;AGMX1;PSCTK1Isotype :
IgGGene ID :
695Clone No :
Swiss Port :
Q06187Molecular weight :
76/80kDaPurification :
Affinity purificationReactivity :
Human MouseApplication :
IHCRecommended dilution :
IHC 1:25-100.Subcellular location :
Cell membrane Cytoplasm Nucleus Peripheral membrane proteinStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.RELATED PRODUCTS
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REFERENCE LIBRARY
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