Anti -TP53 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TP53

Immunogen :

Recombinant protein corresponding to Human p53

Synonym :

TP53;BCC7;LFS1;P53;TRP53;tumor protein p53

Isotype :

IgG

Gene ID :

7157

Clone No :

Swiss Port :

P04637

Molecular weight :

24/30/34/33/38/39/44kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

WB IHC

Recommended dilution :

WB 1: 1000-1:2000. IHC 1:400-1:600.

Subcellular location :

Nucleus Endoplasmic reticulum Mitochondrion

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Tumor protein p53, also known as p53, cellular tumor antigen p53 , phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), which encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, sense cence,DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome.