Anti-PRG2 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PRG2

Immunogen :

Recombinant protein of human PRG2

Synonym :

PRG2;BMPG;MBP;MBP1;proMBP

Isotype :

IgG

Gene ID :

5553

Clone No :

Swiss Port :

P13727

Molecular weight :

23/25kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Cytoplasmic vesicle Secreted Secretory vesicle

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.