Anti-PSMC3 Polyclonal Antibody

No :   K108304P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PSMC3

Immunogen :

A synthetic peptide of Human PSMC3

Synonym :

TBP1;proteasome 26S subunit;ATPase 3

Isotype :

IgG

Gene ID :

5702

Clone No :

Swiss Port :

P17980

Molecular weight :

49kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC 1:50-200.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Component of the 26S proteasome; a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins; which could impair cellular functions; and by removing proteins whose functions are no longer required. Therefore; the proteasome participates in numerous cellular processes; including cell cycle progression; apoptosis; or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
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