PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
PSMC3Immunogen :
A synthetic peptide of Human PSMC3Synonym :
TBP1;proteasome 26S subunit;ATPase 3Isotype :
IgGGene ID :
5702Clone No :
Swiss Port :
P17980Molecular weight :
49kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
WB IHCRecommended dilution :
WB 1:1000-3000. IHC 1:50-200.Subcellular location :
Cytoplasm NucleusStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
Component of the 26S proteasome; a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins; which could impair cellular functions; and by removing proteins whose functions are no longer required. Therefore; the proteasome participates in numerous cellular processes; including cell cycle progression; apoptosis; or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data